知识与财富的链接
细胞质膜微囊(caveolae)为50～100 nm的小囊泡,它们以内陷形式连接在细胞质膜上,并广泛存在于各种类型的细胞.早在40多年前用透射电镜曾观察到此微囊结构.细胞质膜微囊的功能为通过毛细管内皮细胞转运小分子及大分子以及具有“液饮”作用.最近实验表明,Caveolae还参与跨膜信号转导.
Caveolae are 50～100 nm membrane micro-invaginations associated with the plasma membrane of a variety of cells. They were first identified in transmission electron micrographs 40 years ago. Functionally, caveolae are thought to participate in transcellular transport of both small and large molecules across capillary endothelial cells. In addition, caveolae have been postulated to function in potocytosis. More recently, there is growing evidence that caveolae also participate in transmembrane signal transduction.