知识与财富的链接
T-钙黏蛋白(T-cad)是一种新发现的脂联素受体,可以与脂联素六聚体和高分子质量多聚体结合。T-cad在体内许多组织中广泛表达,尤其是心血管系统。T-cad与冠心病密切相关,具有抑制细胞凋亡、阻止动脉粥样硬化、限制血管内膜增生、诱导血管内皮细胞增殖、促进生长因子分泌、促进肌肉再生的作用。因此,探讨T-cad在冠心病中的作用机制,或许能为冠心病的诊疗提供新的思路。
T-cadherin (T-cad) is a newly discovered adiponectin receptor, which can bind to adiponectin hexamer and high molecular weight polymer. T-cad is widely expressed in many tissues in vivo, especially in the cardiovascular system. T-cad is closely related to coronary heart disease, and has the effects of inhibiting cell apoptosis, preventing atherosclerosis, limiting vascular intimal hyperplasia, inducing vascular endothelial cell proliferation, promoting the secretion of growth factors, and promoting muscle regeneration. Therefore, exploring the mechanism of T-cad in coronary heart disease may provide new ideas for the diagnosis and treatment of coronary heart disease.
