Infant sleep problems have become prevalent as complaints of parents to clinicians during the first 2 years of the child's life. This paper reviews (1) identification of multiple etiological sources for infant sleep problems from a systems perspective, (2) the assessment of sleep disturbances, and (3) the applica tion of intervention methods to the appropriate component of system dysfunction. These areas are reviewed by integrating research findings with clinical vignettes from our practice as pediatric sleep clinicians.