<正>Objective To compare the clinical therapeutic effect on perimenopausal depression between the combined treatment with acupuncture at the "thirteen ghost points" and kaixin powder and the single application of kaixin powder.Methods A total of 60 patients with mild perimenopausal depression were randomized into a Chinese medication group(30 cases,2 cases dropping off) and a combined treatment group(acupuncture and Chinese medication,30 cases).In the Chinese medication group,the modified kaixin powder was administered,