This paper presents a detailed analysis of a case of mixed infection with Clonorchis sinensis and feline herpesvirus type 1(FHV-1) in a cat.The cat exhibited jaundice of the visible mucous membranes,abdominal sensitivity upon palpation,dark urine,diarrhea,accompanied by coughing and high fever.Through a comprehensive treatment regimen incorporating deworming,antiviral therapy,hepatoprotective measures,and supportive care,the affected cat achieved successful recovery.The pathogenic mechanism whereby parasitic infection leads to hepatic dysfunction and immunosuppression,potentially inducing the reactivation of latent viruses,is subsequently discussed.This report emphasizes the clinical significance of recognizing mixed infections and provides valuable insights for the clinical diagnosis and management of such complex cases,offering guidance for the diagnosis and treatment of mixed parasitic and viral infections in animals.