National TCM Master WANG Shimin, following the principle of "treating diseases must be based on the root", holds that "deficiency in root and excess in superficiality" is the basic pathogenesis of chronic prostatitis. Deficiency in root is mainly due to spleen and kidney deficiency, and the excess in superficiality is Qi stagnation, blood stasis, dampness heat, among which Qi stagnation is more critical. Professor WANG believes that emotional factors play a key role in this disease. Clinically, he pays attention to the application of soothing liver and relieving depression, and created the experience prescription Sanhe Decoction, which is used for the treatment of chronic prostatitis with the addition and subtraction based on syndrome differentiation.This paper summarized Professor WANG Shimin''s clinical experience in the treatment of chronic prostatitis for clinical reference.