目的探讨燃煤污染型氟中毒病区氟斑牙流行程度与饮用水源化学元素组成的空间分布特征及其关联性。方法 2022年基于贵州省CDC氟斑牙流行程度的调查资料, 在典型燃煤污染型氟中毒区域采集274份原有地表饮用水源, 测定水中氟、钙、镁、铝、钛、铬、锰、铁、镍、铜、锌、砷、硒、钼、镉、钡、铅17种元素的含量;应用Moran’’sI指数、Getis-OrdGi*热点分析饮用水中化学元素的全局空间自相关性以及各元素在局部区域上聚集程度, 并与该区域氟斑牙流行程度进行关联分析。结果除铜、锌、镉元素全局空间自相关Moran’’sI指数为负值外, 其他元素均为正值;氟、钙、铝、钛、砷、钼、镉、铜元素在东南部低海拔地区呈高值聚集;镁、钡、铅、铬、锰、铁元素主要在中部海拔地势过渡区聚集, 锌、硒元素则主要聚集在西南部高海拔地区;水源中锌、硒元素与氟斑牙流行程度呈显著正相关(P<0.05), 而氟、镁、铝、钛、砷、钼、镉、钡、铅元素与之呈显著负相关(P<0.05)。氟、钙、铝、钛、砷、钼元素在东南部地区及锰、铁、钡元素在中部地区呈高-高聚集, 为疾病高发的热点聚集区, 而氟、铝、锰、钼、镉、钡元素在...
Objective To investigate the spatial distribution characteristics and correlation between the prevalence of dental fluorosis and the chemical elemental composition of drinking water sources in coal-fired fluorosis areas. Methods Based on the survey data on the prevalence of dental fluorosis at CDC in Guizhou Province in 2022, 274 original surface drinking water sources were collected in typical coal-fired fluorosis areas, and fluoride (F), calcium (Ca), magnesium (Mg), aluminum (Al), titanium (Ti), chromium (Cr), manganese (Mn), iron (Fe), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium (Se), molybdenum (Mo), cadmium (Cd), barium (Ba), lead (Pb) 17 elements; apply Moran''s I index, Getis-Ord Gi* hotspot analysis of the global spatial autocorrelation of chemical elements in drinking water and the degree of aggregation of each element on the local area, and correlation analysis with the prevalence of dental fluorosis in the region. Results Except for Cu, Zn, and Cd, global spatial autocorrelation Moran''s I was negative, and all other elements were positive. F, Ca, Al, Ti, As, Mo, Cd, and Cu elements showed high values of aggregation in the southeastern low-altitude area; Mg, Ba, Pb, Cr, Mn, and Fe elements were mainly aggregated in the central altitude terrain transition area, Zn and Se elements in water sources are significantly positively correlated with the prevalence of dental fluorosis (P<0.05). In contrast, F, Mg, Al, Ti, As, Mo, Cd, Ba, and Pb elements negatively correlate (P<0.05). Elements in the central region were high-high aggregation, as a hot spot aggregation area with high disease incidence, while F, Al, Mn, Mo, Cd, and Ba elements in the western region were low-low aggregation, as a cold spot aggregation area with a low incidence of fluorosis. Conclusions The risk of population fluoride exposure in surface drinking water sources is shallow. However, the chemical element content of drinking water sources in coal-fired polluted endemic fluorosis areas has prominent spatial geographical distribution characteristics. There is a significant spatial aggregation effect with the prevalence of dental fluorosis, which may play a synergistic or antagonistic effect on the occurrence and prevalence of dental fluorosis.