In order to explore the effects of cold plasma combined with modified atmosphere packaging treatment on storage quality of bayberry, using Yunnan Dongkui fresh bayberry as test material, with bayberry fruits without cold plasma and modified atmosphere packaging treatment as the control, single cold plasma, plain modified atmosphere packaging, and cold plasma combined with modified atmosphere packaging were used to treat the bayberry respectively. The results showed that the cold plasma combined with modified atmosphere packaging could significantly decrease the initial microorganisms load and better inhibit the microbial proliferation during storage, and had no obvious effect on the color of bayberry; and could effectively reduce the decline of soluble solid content and keep a good fruit rate, and also could inhibit the decline of the superoxide dismutase activity in bayberry, delay the oxidative damage and quality deterioration of the fruit, at the same time, the longer treatment time of cold plasma exposure, the better preservation effect. Which can provide theoretical reference for bayberry preservation.