知识与财富的链接
脉管浸润（lymphovascular invasion, LVI）与乳腺癌的不良预后密切相关。术前LVI状态的评估对了解乳腺癌患者病情及其个性化治疗具有重要临床意义。传统影像学特征可用于LVI的评估,包括肿瘤大小、动态对比增强的肿块边缘、内部增强模式、动力学增强曲线、扩散加权成像的边缘征、瘤周间质水肿、皮下脂肪模糊、皮肤增厚等。影像组学可以从数字图像中计算出高通量的定量特征评估研究对象,在LVI的术前预测中具有广阔前景。本文综述了传统影像学及影像组学在乳腺癌LVI评估中的应用,阐述了目前的研究进展、存在的挑战及未来的研究方向,为乳腺癌精准诊疗决策提供了新思路。
Lymphovascular invasion (LVI) is closely associated with the poor prognosis of breast cancer. Evaluating the preoperative LVI status is of significant clinical importance for understanding the condition of breast cancer patients and their personalized treatment. Traditional imaging features such as tumor size, the tumor boundary, internal enhancement pattern, dynamic enhancement curve on dynamic contrast-enhanced, edge signs on diffusion-weighted imaging, peritumoral interstitial edema, subcutaneous fat blurring, and skin thickening can be utilized for evaluating LVI. Radiomics can calculate high-throughput quantitative features from digital images for research subjects, holding great promise in the preoperative prediction of LVI. This review summarizes the applications of conventional imaging and radiomics in assessing LVI in breast cancer. It outlines current research progress, existing challenges, and future research directions, offering new insights for precise diagnosis treatment decisions in breast cancer.
