In this study, the optimal process and its effect on the properties of laser cladding layer with powder feeding methods were investigated. For spherical stainless-steel powder with particle size range of 53~150 μm, the optimized process parameters is that the power of 2600 W, the scanning speed of 8 mm/s, the thickness of 2.0 mm and the lap rate of 50%. Under the optimized process parameters, the microhardness of the cladding layer can reach up to 721.68HV0.2, which was 3.7 times as the substrate. The microstructure of the cladding layer was composed of planar crystal, cellular dendrite and cellular crystal. The grain size varied with the laser energy density. The phases of powder were α-Fe, γ-Fe and M23(B,C)6. The phase of γ-Fe almost disappeared and turned to the Martensite in the cladding layer. Friction and wear-test showed that the friction coefficient of the cladding layer was lower than that of the substrate, which indicates the improvement of wear resistance.