Objective To study the correlation between serum uric acid(SUA) level and catecholamines, blood pressure in college students. Methods A total of 285 from 5 185 college students who participated in the blood pressure survey were selected by using R language stratified random sampling method. According to SUA level, college students were divided into non-hyperuricemia group (177 cases) and hyperuricemia group (108 cases). The plasma catecholamine, biochemical and other indicators were tested and compared between two groups. The correlation was analyzed between SUA and plasma epinephrine(E), norepinephrine(NE), dopamine(DA), systolic blood pressure(SBP), diastolic blood pressures(DBP), heart rate(HR), body mass index(BMI), fasting blood glucose(FBG), serum creatinine(SCr), total cholesterol(TC), triglycerides(TG), high-density lipoprotein cholesterol(HDL-C), and low-density lipoprotein cholesterol(LDL-C). Results In female college students, the plasma E in hyperuricemia group was higher than that in non-hyperuricemia group (P<0.05). In the college students, SBP, DBP, BMI, SCr, SUA, TC, TG, LDL-C in hyperuricemia group were higher than those in non-hyperuricemia group, but HDL-C was lower than that in non-hyperuricemia group (all P<0.05). SUA was positively correlated with plasma E in female college students (P<0.05). The SUA level of all participants was positively correlated with SBP, DBP, BMI, SCr, TG, and LDL-C (all P<0.05), but negatively correlated with HDL-C (P<0.05). Conclusion In the college students, hyperuricemia is closely related with hypertension, obesity, dyslipidemia, and elevated SCr, the higher plasma E level and the greater hyperuricemia risk. The correlation is the strongest between the plasma E and SUA in female college students.