Supercritical fluid extraction（SFE）has receivedwidespread attention for new and green extraction techniques nowadays since it has demonstrated many advantages compared to traditional extraction processes.Aspects such as higher extraction yields,better fractionation capabilities and lower environmental impacts.This present paper reviewed fundamentals of SFE and the most important variables that can affect the extraction process and how to optimize them.And emphasized the application of supercritical fluid extraction in Food Industry such as extract the active component by SFE from plants,animal and food by-products.It was designed to solve complex problems,such as residual organic solvents in traditional extraction process.This article was provided as a tool for us to develop new process at lab and pilot scale,to discover new ways for sample preparation,provided theoretic reference and tech support for new products.