Hydrophobic water-soluble polymer is a kind of water-soluble polymer on the hydrophilic macromolecular chains, which contains a few hydrophobic groups. Study results in the lab indicated that the solution of this polymer showed many excellent properties, such as temperature resistance, salt resistance and shear resistance. The core flooding results indicated that this polymer could increase oil recovery ratio by over 7.62% under high temperature, high mineralization and heavy oil reservoirs, which results in a bright future.