知识与财富的链接
目的探讨慢性肾小球肾炎的最佳治疗方法。方法回顾性总结32例在门诊诊治和随访的未经肾活检病理检查的慢性肾小球肾炎患者的治疗药物种类,疗程和治疗前后24h尿蛋白定量,肾功能等变化。结果32例患者除5例因疗效不佳行肾活检病理检查外,其余27例均有较为显著疗效。24h尿蛋白定量,尿常规等明显改善。而肾功能等生化指标未受影响。结论有些慢性肾小球肾炎患者可以在不做肾活检的情况下进行以药物为主的综合治疗。糖皮质激素等药物是较为有效的,其剂量除肾病综合症按常规剂量外,其余病例均因人因病情而宜。治疗宜早,疗程要长,减量尽量慢。
OBJECTIVE To approach the best therapia of chronic glomerulonephritis. METHOD The clinical data of 32 outpatient cases with chronic glomerulonephritis without renal biopsy were analysed. The data include therapy drugs, treatment time, 24h urine protein and renal insufficiency levels before and after treatment. RESULTS All the cases were more effective expect 5 patients having renal biopsy because of the little effect. 24 hour-proteinuria and urine routine check results were showed apprent change, furthermore, the renal insufficiency were not be effected. CONCLUSIONS: Part of patients with chronic glomerulonephritis can be treated with synthetical drug therapy before renal biopsy. The steroed hormone is effectively. The remedy should be start as soon as possible, the period of treatment should be long and reduction of hormone should be slow when the dosage should be made a difference between patients except nephrotic syndrome which could be according to routine dosage.
