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艾司西酞普兰治疗抑郁症对照研究
Control study of escitalopram and maprotiline in treatment of depression

艾司西酞普兰治疗抑郁症对照研究

ISSN:1005-3220
2008年第18卷第1期
学术交流
张富,毛庆娟,施万平,张志荣,张华彪 ZHANG Fu,MAO Qing-juan,SHI Wan-ping,ZHANG Zhi-rong,ZHANG Hua-biao

目的:探讨艾司西酞普兰治疗抑郁症的疗效及安全性。方法:将63名抑郁症患者随机分为两组,分别给予艾司西酞普兰和马普替林治疗,疗程6周。采用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表病情严重程度(CGI—SI)、治疗中出现的症状量表(TESS)评定疗效及不良反应。结果:艾司西酞普兰与马普替林治疗抑郁症疗效相当,但艾司西酞普兰起效更快,不良反应更少。结论:艾司西酞普兰治疗抑郁症安全有效。

Objective:To detect the efficacy and side effects of escitalopram in the treatment of depresssion.Method:63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks.Hamilton depressive scale(HAMD),clinical global impression severity of illness(CGI-SI)and treatment emergant symptom scale(TESS)were used to evaluate the efficacy and side effects before and after the treatment.Results:There was no significant difference in the efficacy between these two groups.Escitalopram took effect more quickly and less side effects than maprotiline.Conclusion:Escitalopram is a safe and effective antidepressant.

关键词: 艾司西酞普兰抑郁症
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ISSN:1005-3220
2008年第18卷第1期
学术交流

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