目的介绍星点设计基本原理,在大量文献的基础上对星点设计效应面法进行综述,指出该设计的优点和缺点。方法通过查阅国内外近年来的有关资料和文献,对星点设计效应面法在药学试验设计中的应用进行了分析。结果与结论星点设计效应面法具有试验次数少,精确度高,应用方便的特点,该设计方法可以很好地应用于药学领域。
OBJECTIVE To introduce the principle of central composite design(CCD),make an integrate explanation based on a large quantity of documents,and point out the advantages and disadvantages of the CCD.METHODS Analyse the application of central composite design and response surface methodology in pharmacy experiment design by researching the recent domestic and international documents and files.RESULTS AND CONCLUSION Central composite design response surface methodology has the advantages of fewer experiments,convenience and high accuracy.This method can be applied well in the field of pharmacy.