知识与财富的链接
以邻甲苯胺为原料，采用“一锅法”直接合成2-氨基-4-甲基苯并噻唑，获得了最佳工艺条件。该方法避免了通过合成N-邻甲苯基硫脲后再合成产品的两个环节，具有工艺过程简单，操作方便的优势。放大实验结果表明，在最佳工艺条件下，产品的平均收率达到了88％。
The better reaction conditions using one-pot synthetic technology of 2-amino-4-methyl benzothiazole were obtained by raw material of o-toluidine.The synthetic technology left out the two reaction process from o-toluidine to N-(o-tolyl)-thiourea and 2-amino-4-methyl benzothiazole.The one-pot synthetic technology has the advantage of uncomplicated to process and easy to control.The resultes of large scale experiments proved that the average yield was 88%.
