知识与财富的链接
[目的]探讨舌下含服米索前列醇（米索）应用于早孕人工流产术前的可行性、安全性及有效性。[方法]将198例拟行人工流产的妇女随机分为口服米索组96例（A组）、舌下含服米索组102例（B组）。A组术前2h口服米索前列醇400μg,B组术前0．5h舌下含服米索前列醇400μg。观察并比较两组不良反应发生率、宫颈扩张效果、术中出血量、镇痛效果及人工流产综合征发生情况。[结果]B组不良反应发生率低于A组,差异有显著性（x^2=9．62～23．8,P〈0．01）;两组宫颈扩张效果、术中出血量、镇痛效果及人工流产综合征发生率均无显著性差异（P〉0．05）。[结论]米索前列醇舌下含服可作为人工流产术前扩张宫颈的理想给药方法。
［Objective］To investigate the feasibility,safety,efficacy of sublingual misoprostol in artifical abortion. ［Methods］198 women undergoing termination of first-trimester pregnancy were randomly divided into two groups. Women in group A took 400 μg of misoprostol in 2 hours pre-operation、 group B sublingual 400μg of misoprostol in half-hours pre-operation.The side effects of misoprostol, dilatation of cervix、amount of bleeding during operation、painful degree and induced abortion syndrome were observed. ［Results］ The side effects in group B was fewer than in group A（χ2＝9.62～23.8, P<0.01）.There were no significant difference in dilatation of cervix、amount of bleeding during operation、painful degree and induced abortion syndrome between two groups（P>0.05）.［Conclusion］Sublingual misoprostol in half-hours pre-operation is an ideal approach for dilatation of cervix.
