知识与财富的链接
利用室温离子液体[BPY][BF4]作溶剂,将芳醛、乙酰乙酸乙酯和尿素三组分于80℃一锅煮合成了一系列3,4-二氢嘧啶-2(1H)-酮.与传统方法相比,该法操作简单,产率高,反应时间短且环境友好.
3,4-dihydropyrimidine-2(1H)-ones were synthesized in good to excellent yields by one-pot three-component Biginelli condensation of diversity aldehydes,ethyl acetoacetate and urea in room temperature ionic liquid [BPY][BF4] at 80℃.