宏蛋白质组学是近年来出现的一种对天然环境微生态进行大规模蛋白质组学研究工作,其定义为对给定位点的环境微生物群落的所有蛋白质组成进行的即时的大规模的分析。以下将通过分析已有的宏蛋白质组学研究,并结合本研究组的研究经验,对本领域的研究策略、进展情况等加以综述。
Metaproteomics is an emerging proteomics technology to analyze large scale protein expression in environmental microbial ecosystem. It is termed as the large-scale characterization of the entire protein complement of environmental microbial community at a given point in time. This review focuses on the research strategies and the recent applications in this field based on the published reports and in combination with our own research experiences.