知识与财富的链接
用硫酸二烷基酯法合成ＤＭＦ（二甲基甲酰胺）二甲基或二乙基缩醛,产率４０％～７０％。ＤＭＦ二甲基缩醛既能经醇交换反应得到Ｃ４～８醇的ＤＭＦ缩醛,又能和芳香伯胺缩合反应合成甲脒类化合物,产率８０％～９５％。副反应、反应温度和水分是影响产率的主要因素。合成的化合物由元素分析、红外和质谱鉴定。
DMF dimethyl or diethyl acetal was synthesized in 40%- 70% yield by dialkyl sulfatemethod. A competitive pathway and effect of the reaction temperature and water on formation ofacetals were investigated. Some higher dialkyl acetals of DMF and formidine derivatives were achievedby alcoholate interchanging or aminolysis of DMF dimethyl acetal in good to excellent yield. All compounds obtained therein were characterized by their elemental analyses, infrared absorptions and massspectra.