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Identification and determination of (+)-sesamin in Semen Cuscutae by capillary GC and GC-MS

ISSN:1001-8417
2000年第11卷第12期
Yan LI1,Min YE2,Hu Wei LIU1*,Xiu Hong JI2 and Yu Ning YAN2 1Department of Chemistry,Peking University,Beijing 100871 2Beijing University of Chinese Medicine,Beijing 100029 Yan LI,Min YE,Hu Wei LIU,Xiu Hong JI,Yu Ning YAN
Yan LI1,Min YE2,Hu Wei LIU1*,Xiu Hong JI2 and Yu Ning YAN2 1Department of Chemistry,Peking University,Beijing 100871 2Beijing University of Chinese Medicine,Beijing 100029

(+)-Sesamin has been found to have pharmacological effect which can improve activity, prevent aging and has the effect of antihypertension 1-2. Figure 1 shows its chemical structure. (+)-Sesamin has been known to be abundant in sesame originally, but our previous study shows that (+)-sesamin also presents in a Chinese herbal medicine Semen Cuscutae3-4. Gas chromatography (GC) and gas chromatography - mass spectrometry (GC-MS) have been applied for the determination and identification of (+…


(+)-Sesamin was found in Semen Cuscutae for the first time. A rapid and simple approach for the analysis of (+)-sesamin in different sources of Semen Cuscutae is proposed, which used GC-FID for the determination of (+)-sesamin and GC-MS for its identification. The result suggested that this approach could be used to identify Semen Cuscutae from various sources based on the different content of (+)-sesamin in them.

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ISSN:1001-8417
2000年第11卷第12期

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