通过测定典型的多环芳烃类物质苯并(a)芘(BaP)致毒后鱼体内几种重要分子生态毒理学指标的变化,来反映苯并(a)芘致毒对鱼体的影响.结果表明,肝脏ATPase活性降低,GST活性升高,DNA加合物相对标记水平(RAL)也增大,而EROD活性没有明显改变.这说明苯并(a)芘致毒对鱼体正常生命活动产生了重大影响,并具有潜在的致癌性.
This study monitored some important molecular ecotoxicological indicators of fish intoxicated by benzo(a) pyrene(BaP). The decrease of ATPase activity, increase of DNA adduct level and GST activity in fish exposed to BaP compare to control fish received DMSO only were significant. There was, however, no apparent change in EROD activity.The result suggested the important effect of intoxication of BaP on fish.