In recent years, the incidence of infantile repetitive respiratory infection has been increasing. Inorder to prevent and treat this disease, the authors suggest that pathogenesis of this disease is mainlydue to insufficiency of Lung, Spleen and Xidney, which caused the Qi Deficiency and Blood StasisSyndrome, and thus formulated.Yifei Jianshen Mixture(YFJSM). The clinical and experimentalstudy was carried out accordingly. The results showed that this mixture could increase the immunefunction of human body, and improve microcirculation, and has the function of warming up Yang andreplenishing Qi, nourishing blood and activating blood circulation and eventually of preventing andtreating diseases. 305. cases were clinically observed. the total effective rate being 95.1%. The effectof treatmentis obviously better than that of control using Yupingfeng (玉屏风) powder (P<0.01). Theadrenocortical function, plasma nucleotide, immune funtion, microcirculation and others were themain technical indexes of models, which were nearly the same as clinical study. The toxicity test alsoshowed that the YFJSM was non. toxic and had no side effect. The study proved that the mixturewas highly effective and had no side effect.