目的通过18F-FDG SPET/CT扫描诊断食管癌淋巴结转移与术后病理金标准比较,评价18F-FDG SPET/CT诊断的准确性,为临床应用提供理论依据。方法选择2007年1月~2010年6月首程治疗行颈、胸、腹三野淋巴结清扫的胸段食管癌根治术40例患者,术前1周内行18F-FDG SPET/CT检查,将18F-FDG SPET/CT诊断食管淋巴结转移与术后病理诊断进行对比研究。结果全组共清除淋巴结1216枚,平均每例清除淋巴结30.4枚(15~55枚),淋巴结转移率67.5%。SPET/CT诊断食管癌总淋巴结转移的敏感性、特异性及准确性分别为44.4%、84.6%和57.5%。但进一步分析SPET/CT诊断对颈部、上纵隔、下纵隔及腹部区域淋巴结转移的准确性较低,分别为35.0%、50.0%、32.5%和27.5%。其中转移淋巴结短径<0.8cm、0.8~1.2cm和>1.2cm的准确性分别为0.0%、43.8%和84.6%。结论 18F-FDG SPET/CT对食管癌淋巴结转移诊断有较高的特异性,但敏感性及准确性较低;对转移淋巴结短径>1.2cm有较高的准确性。
Objective To evaluate the accuracy of 18F-FDG SPET /CT in diagnosing metastatistic lymph nodes and to provide theoretic base for clinical practices by detecting metastatistic lymph nodes with 18F-FDG SPET/CT compared with the postoperative pathological golden criteria in esophageal carcinoma(EPC).Methods From January 2007 to June 2010,40 patients with esophageal carcinoma in thoracic segments who received initial treatment with 3-field lymphadenectomy were enrolled.All cases received 18F-FDG SPET/CT one wee...