知识与财富的链接
目的:研究刺楸树皮的化学成分,为阐明其活性成分提供依据。方法:采用80%乙醇进行提取,硅胶柱色谱、ODS柱色谱及高效液相制备进行分离纯化,波谱分析(核磁共振氢谱、碳谱和质谱)确定结构。结果:分离鉴定了7个化合物,分别为3-O-α-L-阿拉伯糖-28-O-α-L-鼠李糖-(1→4)-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖基-常春藤皂苷元酯(Ⅰ),刺楸皂苷I(Ⅱ),3-O-α-L-鼠李糖-(1→2)-O-α-L-阿拉伯糖-28-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖常春藤皂苷元酯(Ⅲ),刺楸皂苷B(Ⅳ),丁香树脂醇双葡萄糖苷(Ⅴ),2-甲氧基对苯二酚4-O-[6-O-(4-O-α-L-鼠李糖基)-紫丁香基]-β-D-吡喃葡萄糖(Ⅵ),紫丁香苷(Ⅶ)。结论:化合物Ⅰ,Ⅲ,Ⅴ,Ⅵ为首次从本属植物中分得。
Objective : To study the chemical constituents from Kalopanax septemlobus and to obtain a more understanding of its active principles. Method: Compounds were extracted with 80% ethanol and isolated by column chromatography on silica gel, ODS and prepared with HPLC; the structures were identified by spectroscopic analysis (1H NMR,13C NMR and EIMS). Result: Seven compounds were obtained and identified as 3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl ester of hederagenin (Ⅰ), kalopanaxsaponin I (Ⅱ), 3-O-α-L-rhamnopyranosyl-(1→2)-O-α-L-arabinopyranoside-28-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl ester of hederagenin (Ⅲ), kalopanaxsaponin B (Ⅳ), liriodendrin(Ⅴ),2-methoxyhydroquinone 4-O-[6-O-(4-O-α-L-rhamnopyranosyl)-syringyl]-β-D-glucopyranoside (Ⅵ), syringin (Ⅶ). Conclusion : Compound Ⅰ, Ⅲ, Ⅴ, Ⅵ were obtained from this cdrus plant for the first time.
