目前,我国对天然活性成分构效关系的研究方面相当不够,是一种巨大的资源浪费。对有苗头的活性单体进行构效关系研究,将活性好的衍生物开发成新药,具有重要的战略意义。本文主要探讨进行天然活性成分的构效关系研究的概况、必要性和方法。
Nowadays,the study on the stuctrure-activitity relationship(SAR)of natural active constituents is not enough in China and this means a great waste of resources.Therefore,it is of vital strategical significance to develop most active derivatives into new drugs through SAR study of potential active contituents.This article mainly discusses the summary,necessity and method of SAR study of natural active constituents.