This study is designed to explore the relationship between pulse graph traits and pathological information of coronary heart disease (CHD) patients, in an attempt to find out both pathological and physiological indexes that are associated with pulse graph parameters. In this study, 1) CHDpatients' pulse graph were collected using the pulse detection system, and the pulse traits analyzed through the time domain method. CHD patients' ultrasound cardiograph were collected using Megas Doppler multicolor ultrasound instrument, and the coronary angiography (CAG) was conducted through Judkin method. 2) We analyzed the relationship between time domain parameters and pathological information, using analytical method of canonical correlation. Study results showthat 1) there is a positive correlation between magnitude of coronary artery stenosis and such pulse graph parameters as h3/h1,w1/t,h3,t5/t4. w1/t is, in particular, closely associated with the magnitude of coronary artery stenosis. Aclose relationship is also seen between h1,h5,h5/h1 and Doppler ultrasonic index of heart; 2) They are negative correlation. In the context of blood- fat ingredients, a change in the lowdensity lipoprotein (LDL) is closely associated with h1,h5 and h5/h1 of pulse graph in CHD.We believe there are certain correlations between pulse graph parameters and coronary artery stenosis and ultrasound cardiograph. Study results indicate that pathological changes of coronary artery and heart could be a material base to shape up pulse graph traits in CHDpatients. In addition, Pulse Diagnosis featured with non- invasive detection provides a theoretical support.