知识与财富的链接
目的：探讨莫西沙星所致不良反应的类型及其特点,为临床安全用药提供参考。方法：在中国科技期刊数据库（维普资讯）和中国期刊全文数据库（中国知网）中,以＂莫西沙星＂和＂不良反应＂为关键词,搜索2005年～2011年11月莫西沙星所致不良反应文献,并进行统计分析。结果：收集到62例莫西沙星导致的不良反应,主要类型有神经系统反应（28.4%）、过敏反应（21.6%）、心血管系统反应（14.9%）、消化系统反应（10.8%）、呼吸系统反应（6.8%）等。70岁以上的患者占46.8%（29/62）,高于其他年龄段。静脉滴注给药者占59.7%（37/62）。结论：临床应高度重视莫西沙星的不良反应,加强用药监护。
Objective:To explore the type and characteristics of adverse drug reactions(ADRs) induced by moxifloxacin to provide reference for the clinical rational use of drugs.Methods:Based on the VIP and CNKI database,literatures about moxifloxacin-induced ADRs from 2005 to 2011 were collected and statistically analyzed.Results:In 62 case of patients,main clinical manifestations of moxifloxacin-induced ADRs were nervous system reactions(28.4%).allergic reactions (21.6%),cardiovascular system reactions(14.9%),digestive system reactions(10.8%),respiratory system reactions (6.8%),etc.The patients aged more than 70 were 29 cases,accounting for 46.8%.Intravenous drips were 37 cases,accounting for 59.7%.Conclusion:In clinical application,more attention should be paid to the moxifloxacin-induced ADRs, and the strict monitor of the drug use should be strenghtened.
