Tamsulosin hydrochloride is widely used for the treatment of lower urinary tract symptoms of benign prostatic hyperplasia, requiring long-term medication. It reduces adverse reactions of hypotension and dizziness by rapid absorption from oral intake. The sustained-release (SR) formulation is recommended for clinical application. Currently in domestic and foreign market, SR products mainly include SR capsules and SR tablets, like Flomax^® and Harnal^®. The domestic market mainly uses the originally developed Harnal^® SR capsules. In accordance with the drug''s potential market, more and more SR studies have been done. This article reviews the research progress of tamsulosin hydrochloride sustained-release preparation.