Russia's Mars probe Phobos-Grunt together with China's first Mars probe Yinghuo-1 were launched into Low Earth Orbit (LEO) on November 9, 2011. Unfortunately, the main probe failed to fire its thrusters and transfer its orbit as planned after 159 minutes, eventually the trip to Mars was terminated. The most likely cause of the accident investigated by Russian Space Agency (RSA) was that RAM chips in onboard control computers worked wrong when hit by cosmic heavy charged particles, which sequently led to the two computers restart and eventually disturbed the probe totally. However experts on satellite radiation hardness casted lot of doubt on the statement that LEO probe can be effected by Single-Event Effects (SEE) resulting from space radiation particles in so short period of time. Based on information of the victim RAM components disclosed by RSA, experiment tests and calculations were performed for K6R4016V1D chip to predict SEE rate when applied in LEO. Finally, possibility for SEE to cause the failure of Phobos-Grunt probe was discussed.