Taking into consideration that Christians and Muslims in sub-Saharan Africa live intermingled in family, clan or ethnic groups, this article takes cognizance of the effect of the teachings of each tradition about their own identity and their perception of the other. It also seeks to take into account the Roman Catholic principles of inter-religious dialogue as enunciated by the Second Vatican Council in the documents Nostra Aetate and the Declaration on the Relation of the Church to Non-Christians, as well as Unitatis Reintegratio, the Decree on Ecumenism, and Dominus Iesus. In view of the fact that these are seen as a source of tension, the question arises as to whether they are being interpreted correctly or applied in the spirit intended.