知识与财富的链接
[目的]] 通过正交设计筛选胡黄连的提取工艺,优化出最佳工艺参数。[方法]以提取液中胡黄连苷Ⅰ、Ⅱ转移率及出膏率的加和进行综合评价,采用L9(34)正交实验优选最佳提取工艺。[结果]胡黄连最佳提取工艺为原药材最粗粉浸泡24 h,以每分钟1.5 mL的流速渗漉,收集16倍量的渗漉液。[结论]优选的胡黄连提取工艺合理可行,为实际生产提供参考。
[Objective] To optimize the extraction process of Rhizoma Picrorhizae by an orthogonal experiment and to determine the best extraction parameters. [Methods] The L9(34) orthogonal test was employed based on a multiple criteria comprehensively evaluating the yields of picroside I, picroside II, and total extracts. [Results] The optimum extraction process was characterized as: soaking the crude rhizome powders for 24 h and percolating them with 1.5 mL/min of the flow rate and 16 folds of extraction volume were collected. [Conclusion] The extraction technique is stable and available.This study provides an experimental basis for the industrial production of Rhizoma Picrorhizae.
