General biology is the elementary course for biological science in colleges and universities. It contains a mass of contents that involve almost all the subjects of life sciences. Some teaching contents are uninteresting with strong theory, and some contents are already learned from senior high school, which makes the students’ learning interests not very high. They didn’t realize the importance of course learning. To some extent, the quality of biology education was low because of this activity. The Nobel Prize in Physiology or Medicine represents the highest level of life science and medical science and has a significant attraction for the students. By the combination of the Nobel Prize in general biology teaching, including the story of the gainers, progress of investigation, and the design of experiments, it may inspire students’ studying interest, improve students’ understanding and knowledge obtaining, and cultivate students’ creative thinking ability. It will be of great importance in general biology teaching.