知识与财富的链接
背景：颈椎前路减压融合内固定术是治疗颈椎病的有效手段。但接骨板内固定在增加融合率的同时常导致一些并发症。目的：探讨一种新型零切迹颈椎前路椎间融合固定系统（Zero-P）治疗颈椎病的疗效，以降低术后并发症的发生率。方法：2010年6月至2011年6月对51例颈椎病患者行颈椎前路减压融合术。A组33例使用椎间融合器联合钛板固定；B组18例使用Zero-P。比较两组手术时间，术中出血量，JOA评分及改善率，NDI评分，术后融合率，术后并发症发生率。结果：A组随访9～18个月，平均12个月：B组随访6～19个月，平均10个月。两组手术时间，术中出血量，JOA评分及改善率，NDI评分，融合率均无显著差异（P〉O．05）。但B组术后并发症发生率明显低于A组（尸〈0．05）。结论：Zero-P能降低术后并发症的发生率，尤其是吞咽不适的发生，是一种值得进一步临床应用的颈椎前路椎间融合固定系统。
Background： Anterior cervical discectomy and fusion （ACDF） is an effective treatment for cervical spondylosis. But inter- nal fixation with plate often results in some postoperative complications. Objective： To evaluate the clinical outcomes of a new anterior cervical fusion and fixed system （Zero-Profile） in the treatment of cervical spondylosis so as to decrease the postoperative complications. Methods： A total of 51 patients with cervical spondylosis were treated with ACDF between June 2010 and June 2011. Cage and titanium plate implantation were used in 33 patients of group A. Zero-Profile anterior cervical fusion and fixed system was applied in 18 patients of group B. Operation time, intraoperative blood loss, JOA and NDI scores, fusion rate and complications were compared between groups. Results： The mean follow-up period of group A was 12 months （range, 9 to 18 months）. And the mean follow-up period of group B was10 months （range, 6 to 19 months）. There were no significant differences in operation time, intraoperative blood loss, JOA and NDI scores, and fusion rate （P〉0.05）. But the incidence of postoperative complications of group B was significantly lower than group A （P〈0.05）. Conclusions： Zero-Profile anterior cervical fusion and fixed system can reduce the incidence of postoperative complications, especially the incidence of dysphagia.
