知识与财富的链接
目的:探讨慢性前列腺炎患者前列腺液16S rDNA检测的临床意义。方法:对116例慢性前列腺炎患者前列腺液采用PCR方法检测其16S rDNA,比较不同亚型前列腺炎的16S rDNA阳性率并分析其相关性。结果:29例Ⅱ型前列腺炎前列腺液16S rDNA PCR均阳性,阳性率100%;87例Ⅲ型前列腺炎前列腺液16S rDNA PCR阳性71例,阳性率82%,其中ⅢA型前列腺炎前列腺液PCR阳性率94%(45/48),ⅢB型前列腺炎前列腺液PCR阳性率67%(26/39)。结论:16S rDNA的检测可能成为慢性前列腺炎分型的一个指标。
OBJECTIVE: To evaluate the expression and significance of 16S rDNA in prostatic secretions (EPS) of chronic prostatitis. METHODS: 16S rDNA was detected in EPS of 116 patients with chronic prostatitis by PCR. RESULTS: 16S rDNA were positively expressed in all 29 cases of II type chronic bacterial prostatitis and 71 out of 87 cases of III type chronic prostatitis (82%). The positive rates were 94% (45/48) and 67% (26/39) in lIIA and IIIB chronic prostatitis respectively. There was a statistical difference in 16S rDNA positive rate between IIIA and IlB chronic prostatitis (P < 0.01). CONCLUSION: Detection of 16s rDNA may be a useful index for the diagnosis and classification of chronic prostatitis.
