目的探讨发声任务对功能磁共振成像的影响,并发展一系列数据处理方法,从而更完全地校正发声伪影.方法 8名被试在磁共振扫描过程中执行汉字阅读任务, 以200个汉字作为刺激材料.每名被试完成两个发声阅读序列和两个默声阅读序列.采用三种不同的数据处理方法,其中前两种方法已有报道,而最后一种方法为本文首次提出.结果与前两种方法相比,本文提出的方法更完全地校正了发声伪影的影响,信号的损失也较小.结论利用适当的数据处理方法,功能磁共振研究中发声伪影可以得到有效校正;发声任务可以应用于功能磁共振成像研究.
Objective To investigate the effect of overt responses on functional magnetic resonance imaging (fMRI) and to develop a more reliable data analysis method for elimination of artifacts. Methods Eight subjects performed Chinese characters reading tasks during scanning, in which 200 Chinese characters severed as stimuli. Each of the subjects completed 2 overt scanning sessions and 2 covert sessions. We compared different data analysis methods for correction of the artifacts. The first two was reported in literature and the last one is newly developed in present study. Results The method developed in this study eliminated the artifacts induced by overt responses during fMRI scanning more completely than those of the others, but the signal loss was less significant. Conclusion By means of more sophisticated data analysis, the artifacts induced by the overt responses during fMRI scanning can be effectively eliminated. Consequently, the overt responses can be introduced to the fMRI studies.