知识与财富的链接
目的 :为阐明黑面神的有效成分 ,对其地上部分进行了系统的化学成分研究。方法 :95%乙醇提取、溶剂萃取、硅胶柱色谱、SephadexLH-20柱色谱。结果 :分离得到 7个化合物 ,经光谱方法鉴定为aviculin [(+)-iso-lariciresinol 9′-rhamnopyranoside,1]、木栓醇 (friedelan-3β-ol,2 )、无羁萜 (friedelin ,3)、arborinone(4)、isoarborinol(5 )、5 羟基 7,8,4′-三甲氧基黄酮 (5 hydroxy 7,8,4′-trimethoxy flavone,6 )和 2 ,4-二羟基 6-甲氧基 3-甲基 苯乙酮 (2 ,4-dihydroxy-6-methoxy-3-methyl acetophenone,7)。结论 :7个化合物均为首次从黑面神属植物中分离得到 ,aviculin也是首次从大戟科中分离得到。
OBJECTIVE: To investigate the chemical constituents from the aerial parts of Breynia fruticosa. METHOD: Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chemical evidence and spectral methods. RESULT: Seven compounds were obtained and identified by spectroscopic methods and compared with authentic samples as aviculin [(+)-isolariciresinol-9'-rhamno-pyranoside], friedelan-3beta-ol, friedelin, arborinone, isoarborinol, 5-hydroxy-7,8,4'-trimethoxy flavone, 2,4-dihydroxy-6-methoxy-3-methyl-acetophenone. CONCLUSION: All compounds were firstly isolated from B. genus, furthermore, aviculin was isolated from Euphorbiaceae for the first time.
