研究了甲基丙烯酸甲酯的加溴、脱溴化氢的反应,它与通常脱溴化氢的反应不同,它是先脱去一分子的溴化氢,接着是甲醇钠的亲核加成脱溴,再加一分子的甲醇.得到总收率为71.6%的3,3-二甲氧基-2-甲基-丙酸甲酯.
This study investigated the bromination and dehydrogenbromi-nation of methyl methacrylate.By contrast to the common dehydrogenbromi-nation,this reaction process includes three sequences,releasing one hydrogen bromide,nucleophile addition of sodium methanolate and addition of one methanol.Subsequently,Methyl 3,3-dimethoxy-2-methylpropionate was obtained in high yield.