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人巨细胞病毒感染对非特异性下腰痛患者内皮功能的影响
Human Cytomegalovirus Infection and Endothelial Function Disorder in Patients with Nonspecific Low Back Pain

人巨细胞病毒感染对非特异性下腰痛患者内皮功能的影响

ISSN:1006-9771
2007年第13卷第1期
临床研究
吴建贤[1],王斌[1],李红[2],胡勇[3],胡雪莹[3],王明丽[3] WU Jian-xian ,WANG Bing, LI Hong,et al.
  1. 安徽医科大学第一附属医院康复医学科,安徽,合肥市,230022
  2. 安徽省立儿童医院小儿神经康复科,安徽,合肥市,230051
  3. 安徽医科大学基础医学院病原学教研室,安徽,合肥市,230031
Department of Rebabilitation Medicine, Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China

目的探讨内皮功能异常与人巨细胞病毒(HCMV)感染致非特异性下腰痛(NLBP)的关系,及其在NLBP发病中的作用。方法NLBP组50例,对照组36例,检测尿沉渣HCMV-DNA和包涵体,外周血HCMV-IgM、IgG和内皮素水平。结果NLBP组尿HCMV-DNA和包涵体,血HCMV-IgM、IgG阳性率高于正常对照组(P<0·05)。NLBP组内皮素水平增高(P<0·05)。结论NLBP常伴有HCMV感染及内皮功能异常。

ObjectiveTo study the relationship between Human Cytomegalovirus (HCMV) infection and endothelial function disorder and its possible role in nonspecific low back pain (NLBP).MethodsHCMV-DNA, -IgM, -IgG, HE stain, endothelin (ET) were detected in 50 patients with NLBP and 36 healthy people without NLBP(non-NLBP group).ResultsThe positive rate of HCMV-DNA,-IgM,-IgG, HE stain were higher in NLBP group than that in non-NLBP group(P<0.05), as well as the levels of ET(P<0.05).ConclusionHCMV infection may relate with NLBP, and ET may play an important role in it.

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ISSN:1006-9771
2007年第13卷第1期
临床研究

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