知识与财富的链接
为研究评价先天性主动脉瓣狭窄 (AS)球囊瓣膜成形术 (PBAV)的效果。方法 于 1986年 12月 - 1999年 8月应用PBAV术治疗了 2 7例AS病人 ,年龄 2 .5- 12岁 (平均 6 .0 9± 2 .2 6岁 )。PBAV术球 瓣比值 :发育良好型者 (19例 )为 0 .95± 0 .0 8;发育不良型 (8例 )则为 1.0 0± 0 .11。术前后测定左室和升主动脉压力及跨主动脉瓣压力阶差 (ΔP)。出院后多普勒超声心动图随访以监测跨主动脉瓣ΔP。结果 发育良好型者 15例 (占 78.9% )即刻效果良好 ,随访中有 4例 (2 6 .7% )ΔP回复至 50mmHg以上 ;发育不良型 4例 (占 50 % )效果良好 ,其中随访中有 3例回升 (占 75.0 % )。 2 7例PBAV后无一例有轻度以上主动脉瓣返流及其它并发症结论 PBAV术是一种对AS有效、安全的替代外科瓣膜切开的介入性治疗方法 ,而且发育良好型AS较发育不良型效果好
OBJECTIVE: To assess the effect of the balloon valvuloplasty for for congenital valvular aortic stenosis (AS) in children. METHODS: A total of 27 (mean age 6.09 years) children with AS accepted the treatment of percutaneous balloon aortic valvuloplasty (PBAV). The ratios of balloon/valve were 0.95 +/- 0.08 for 19 cases of typical AS and 1.00 +/- 0.11 for 8 cases of hypoplastic AS. The patients were evaluated by the gradients across aortic valves in pre- and post-PBAV and by echocardiogram during the follow-up period. RESULTS: Fifteen of 19 (78.9%) cases of typical AS had a better outcome and the gradient of the remaining 4 cases (26.7%) had increased after follow-up (delta P > 50 mm Hg). Four of 8 (50.0%) cases of hypoplastic AS had satisfactory responses and the gradient of the remaining 3 cases (75.0%) rose. There was no moderate to severe aortic insufficiency (AI). CONCLUSION: The balloon aortic valvuloplasty provides safe and significant hemodynamic and clinical improvement in pediatric patients. The outcome of PBAV for typical AS is better than for hypoplastic AS.